Dmitry I. Trukhan , Maria Yu. Rozhkova , Inna A. Viktorova
Abstract
An important component of rational pharmacotherapy is drug safety – one of the priority basic areas of modern medicine and pharmacy. Often, the presence of side effects of a drug, despite its effectiveness, is an obstacle to its use or requires careful monitoring during therapy. As an example of this thesis, we can consider amiodarone, the best-known and most prescribed antiarrhythmic drug, which has been used in clinical practice since the 60s. “Typical” problems include the effect of amiodarone on the thyroid gland, while the most serious – pulmonary (amiodarone-induced pneumonitis or interstitial fibrosis of the lungs) and liver – are underestimated in practice by doctors prescribing amiodarone as a 1st choice drug. This review examines the dermatological side effects of amiodarone.
Key words: amiodarone, side effects, exfoliative dermatitis, photosensitivity, photosensitivity, non-melanoma skin cancer, blue man syndrome, alopecia, drug-induced lupus erythematosus.
Key words: amiodarone, side effects, exfoliative dermatitis, photosensitivity, photosensitivity, non-melanoma skin cancer, blue man syndrome, alopecia, drug-induced lupus erythematosus.
About the Author
Dmitry I. Trukhan 1 , Maria Yu. Rozhkova 1 , Inna A. Viktorova 11 Omsk State Medical University, Omsk, Russia
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For citation:Trukhan D.I. Rozhkova M. Yu., Viktorova I.A. Amiodarone-induced skin lesions. Clinical review for general practice. 2023; 4 (7): 106–111 (In Russ.). DOI: 10.47407/kr2023.4.8.00338
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