Abstract
Aim. To study the perineal tissue state during the development of PFD.
Methods. The prospective randomized comparative cohort study involved 155 women, who contacted the Department of Gynecology for elective surgical treatment. All patients underwent standard clinical and instrumental assessment for gynecological patients: history taking, physical ex-amination, advanced gynecological assessment, pelvic ultrasound. The assessment program was expanded to complex perineological examination including pelvic floor evaluation according to the method by L.R. Toktar, perineal manometry using the iEase XFT-0010 perineometer (according to the unit user manual), transperineal ultrasound. In addition, evaluation of vaginal biotope and morphological assessment of the levator com-plex were performed.
Results. According to the data obtained, abnormal vaginal biotope is the major atypical PFD symptom. This condition is recurrent. The vaginal wall loss of elasticity and abnormal collagenization result in the more profound perineal tissue alterations. Morphological assessment of perineal tissues has revealed levator ani inflammation in 20% of cases and fibrosis in 100% of cases.
Conclusions. Recurrent vaginal biocenosis abnormality is a clinical symptom of PFD. Vaginal dysbiosis results in morphological alterations in the vaginal wall structure and probably in the entire levator complex.
Key words: pelvic floor dysfunction, genital prolapse, pelvic floor, vaginal biocenosis.
For citation:Toktar L.R., Orazov M.R., Pak V.E., Gaifullin R.F., Mikhaleva L.M., Midiber K.Yu., Samsonova I.A., Kamarova Z.N., Dostieva Sh.M. Pathogenetic features of pelvic floor dysfunction development in women of child-bearing age. Clinical review for general practice. 2023; 4 (9): 49–58 (In Russ.). DOI: 10.47407/kr2023.4.9.00308
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