Abstract
Aim. To develop indications for paraurethral administration of DELIGHT® G® hyaluronic acid-based gel for stress urinary incontinence and to evaluate its effectiveness and safety.
Materials and methods. The study involved 35 patients aged 45–55 with mild stress incontinence.
Results. The effectiveness of urinary incontinence therapy was 97.1% (n=34). All patients underwent functional tests, uroflowmetry, profilome-try and ultrasound examination of the paraurethral area before and after paraurethral injection of hyaluronic acid-based gel. Uroflowmetry data: before the introduction of the gel, the average value of Qmax 27±1.5 ml/sec and Q average 13.5±2.7 ml/sec, immediately after the paraurethral in-jection of the gel, Qmax 19±2.1 ml/sec and Q average 12.6±1.6 ml/sec and after month Qmax 20±2.3 ml/sec and Q average 11.9±1.9 ml/sec. Profilom-etry data: the average length and functional length of the urethra were 34±0.9 mm and 31±0.8 mm, respectively, which indicates that this study is not informative. According to ultrasound examination of the paraurethral area, after the introduction of a gel based on hyaluronic acid into the paraurethral area, signs of urethral hypermobility and sphincter insufficiency are leveled.
Conclusions. Paraurethral injection of hyaluronic acid-based gel can be considered as first-line therapy stress urinary incontinence for patients with initial manifestations of stress urinary incontinence.
Key words: stress urinary incontinence, stress urinary incontinence, paraurethral administration, fillers, hyaluronic acid, hypermobility of the urethra, co-optation of the urethral mucosa.
For citation:Balan V.E., Tikhomirova E.V., Chechneva M.A., Kapitanova O.V., Orlova S.A., Zhuravel A.S., Kruchinina E.V., Petrukhin V.A. The minimally invasive method for treatment of stress urinary incontinence in women. Clinical analysis.. Clinical review for general practice. 2023; 4 (9): 41–48 (In Russ.). DOI: 10.47407/kr2023.4.9.00307
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