Lower respiratory tract infections in patients with comorbidities

Leonid I. Dvoretsky

For citation:

Abstract

Comorbidities are an important factor of the various infectious respiratory diseases emergence, complications development and prognosis. The most frequent comorbidities affecting the course and outcome of respiratory infections are the following: cardiovascular disease (heart failure, various types of coronary artery disease, cerebrovascular disease), chronic obstructive pulmonary disease, diabetes mellitus, obesity. The paper reports data on the discussed comorbidities impact on the course and outcome of bacterial and viral respiratory infections, inter alia in patients with COVID-19.

Key words: comorbidity, lower respiratory tract infections, pneumonia, СОVID-19.

References

1. Chuchalin A.G. Khronicheskaia obstruktivnaia bolezn' legkikh i soputstvuiushchie zabolevaniia. Chast' I. KhOBL i porazheniia serdechno-sosudistoi sistemy. RMZh. 2008; 2: 58 (in Russian).

2. Gao HN, Lu HZ, Cao B et al. Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med 2013; 368: 2277–85.

3. Luna СМ, Palma I, Niederman М et al. The Impact of Age and Comorbidities on the Mortality of Patients of Different Age Groups Admitted with Community-acquired Pneumonia. Ann Am Thorac Soc 2016; 13 (9): 1519–26. DOI: 10.1513/AnnalsATS.201512-848OC

4. Guan W, Liang W, Zhao Y et al. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. Eur Respir J 2020; 55: 200.

5. Xiao K, Su LX, Han BC et al. Analysis of the severity and prognosis assessment of aged patients with community-acquired pneumonia: a retrospective study. J Thorac Dis 2013; 5 (5): 626–33.

6. Ishiguro T, Takayanagi N, Yamaguchi S et al. Etiology and factors contributing to the severity and mortality of community-acquired pneumonia. Intern Med 2013; 52 (3): 317–24.

7. Corrales-Medina VF, Musher DM, Wells GA. Cardiac complications in patients with community-acquired pneumonia: incidence, timing, risk factors, and association with short-term mortality. Circulation 2012; 125 (6): 773–81.

8. Welte T. Community-acquired pneumonia. Internist (Berl) 2009; 50 (3): 331–9.

9. Fujiki R, Kawayama T, Ueyama T et al. The risk factors for mortality of community-acquired pneumonia in Japan. J Infect Chemother 2007; 13 (3): 157–65.

10. Ramirez J, Aliberti S, Mirsaeidi M et al. Acute myocardial infarction in hospitalized patients with community-acquired pneumonia. Clin Infect Dis 2008; 47: 182–7.

11. Perry TW, Pugh MJ, Waterer GW et al. Incidence of cardiovascular events after hospital admission for pneumonia. Am J Med 2011; 124: 244–51.

12. Alon D, Stein G, Korenfeld R, Fuchs S. Predictors and Outcomes of Infection-Related Hospital Admissions of Heart Failure Patients. PLoS ONE 2013; 8 (8): e72476. DOI: 10.1371/journal.pone.0072476

13. Yang J, Zhenga Y Gou Х et al. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis 2020; 94: 91–5.

14. Shi О, Zhang Х, Jiang F et al. Clinical Characteristics and Risk Factors for Mortality of COVID-19 Patients With Diabetes in Wuhan, China: A Two-Center. Retrospective Study. Diabetes Care 2020; 43 (7): 1382–91.

15. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese center for disease Control and prevention. J Am Med Assoc 2020 (in press). Bansal М. Cardiovascular disease and COVID-19. Diabetes & Metabolic Syndrome: Clin Res Rev 2020; 14: 247e250.

16. Falguera M, Martin M, Ruiz A et al. Community-acquired pneumonia as the initial manifestation of serious underlying diseases. Am J Med 2005; 118 (4): 378–83.

17. Mannino DM, Davis KJ, Kiri VA. Chronic obstructive pulmonary disease and hospitalizations for pneumonia in a US cohort. Respir Med 2009; 103 (2): 224–9.

18. Müllerova H, Chigbo C, Hagan GW et al. The natural history of community-acquired pneumonia in COPD patients: a population database analysis. Respir Med 2012; 106 (8): 1124–33.

19. Baimakanova G.E., Zubairova P.A., Avdeev S.N., Chuchalin A.G. Osobennosti klinicheskoi kartiny i techeniia vnebol'nichnoi pnevmonii u patsientov s khronicheskoi obstruktivnoi bolezn'iu legkikh. Pul'monologiia. 2009; 2, 33–41 (in Russian).

20. Lin S, Ji B, Shih Y et al. Comorbid pulmonary disease and risk of community-acquired pneumonia in COPD patients. Int J Tuberc Lung Dis 2013; 17 (12): 1638–44.

21. Li X, Li Q, Si L, Yuan Q. Bacteriological differences between COPD exacerbation and community-acquired pneumonia. Respir Care 2011; 56 (11): 1818–24.

22. Reissig A, Mempel C, Schumacher U et al. Microbiological diagnosis and antibiotic therapy in patients with community-acquired pneumonia and acute COPD exacerbation in daily clinical practice: comparison to current guidelines. Lung 2013; 191 (3): 239–46.

23. Restrepo MI, Mortensen EM, Pugh JA, Anzueto A. COPD is associated with increased mortality in patients with community acquired pneumonia. Eur Respir J 2006; 28: 346–51.

24. Cherniaev A.L. Diagnosticheskie oshibki v pul'monologii. Pul'monologiia 2005; 3: 5–11 (in Russian).

25. Sethi S. Infection as a comorbidity of COPD. Eur Respir J 2010; 35: 1209–15.

26. Setter N, Peres M, de Almeida B et al. Charlson comorbidity index scores and in‐hospital prognosis of patients with severe acute respiratory infections. Intern Med J; 2020; 50: 691–7. DOI: 10.1111/imj.14398

27. Ernst Р, Gonzalez А, Brassard Р, Suissa S. Inhaled Corticosteroid Use in Chronic Obstructive Pulmonary Disease and the Risk of Hospitalization for Pneumonia. Am J Respir Crit Care Med 2007; 176 (2): 162–6. DOI: 10.1164/rccm.200611-1630OC

28. Long-term Use Of Popular Inhalers Increases Risk Of Pneumonia For COPD Patients 12, 2009, Wake Forest University Baptist Medical Center. http://www.sciencedaily.com

29. Von Baum H, Welte T, Marre R et al; for the Capnetz Study Group. Community-acquired pneumonia through enterobacteriaceae and Pseudomonas aeruginosa: diagnosis, incidence and predictors. Eur Respir J 2010; 35: 598–615.

30. McKeever Т, Harrison Т, Hubbard R, Shaw D. Inhaled Corticosteroids and the Risk of Pneumonia in People With Asthma A Case-Control Study. CHEST 2013; 144 (6): 1788–94.

31. Kornum JB, Thomsen RW, Riis A et al. Type 2 diabetes and pneumonia outcomes: a population-based cohort study. Diabetes Care 2007; 30 (9): 2251–7. DOI: 10.2337/dc06-2417

32. Mokdad AH, Ford ES, Bowman BA et al. Prevalence of obesity, diabetes, and obesity-related health risk factors. JAMA 2003; 289: 76–9.

33. Hainer V, Zanrazilova Н, Kunesova М et al. Obesity and Infection: Reciprocal Causality. Physiol Res 2015; 64 (Suppl. 2): S105–S119.

34. Dhurandhar NV, Israel BA, Kolesar JM et al. Adiposity in animals due to a human virus. Int J Obes 2000; 24: 989–96.

35. Dhurandhar NV, Whigham LD, Abbott DH, Schulz-Darken NJ. Human adenovirus Ad-36 promotes weight gain in male rhesus and marmoset monkeys. J Nutr 2002; 132: (10): 3155–60.

36. Ashburn DD, DeAntonio A, Reed MJ. Pulmonary system and obesity. Crit Care Clin 2010; 26: 597–602.

37. Koenig SM. Pulmonary complications of obesity. Am J Med Sci 2001; 321: 249–79. DOI: 10.1097/00000441-200104000-00006

38. Beal M, Chesson A, Garcia T et al. A pilot study of quantitative aspiration in patients with symptoms of obstructive sleep apnea: comparison to a historic control group. Laryngoscope 2004; 114: 965–68. DOI: 10.1097/00005537-200406000-00002

40. Jedrychowski W, Maugeri U, Flak E et al. Predisposition to acute respiratory infections among overweight preadolescent children: an epidemiologic study in Poland. Public Health 1998; 112: 189–95. DOI: 10.1038/sj.ph.1900438

41. Baik I, Curhan GC, Rimm EB. A prospective study of age and lifestyle factors in relation to community-acquired pneumonia in US men and women. Arch Intern Med 2000; 160: 3082–88.

42. Phung DT, Wang GZ, Rutgerford S et al. Body mass index and risk of pneumonia: a systematic review and meta-analysis. Obes Rev 2013; 14: 839–57. DOI: 10.1111/obr.12055

43. Martínez A, Soldevila N, Romero-Tamarit A et al. Risk factors associated with severe outcomes in adult hospitalized patients according to influenza type and subtype. PLOS ONE 2019; 14 (1): e0210353

For citation:Dvoretsky L.I. Lower respiratory tract infections in patients with comorbidities. Clinical review for general practice. 2020; 1: 29–34. DOI: 10.47407/kr2020.1.1.00005

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Clinical review for general practice