Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
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FULLSCREEN > Archive > 2022 > Vol 3, №3 (2022) > Clinical case: Hepatoblastoma of the liver in the age not typical for hepatoblastoma

Clinical case: Hepatoblastoma of the liver in the age not typical for hepatoblastoma

T.B. Tuyakova , V.S. Rakhmetova , G.A. Abai

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Abstract

Hepatoblastoma is a rare malignant tumor. One case of hepatoblastoma per 1 million of children under the age of 15 is diagnosed annually in the Republic of Kazakhstan (RK), which corresponds to 5–6 cases per year. In 90% of cases the tumor is diagnosed in children under the age of 5 and has two peaks of incidence: the first peak at birth or within the first month of life, and the second peak between the ages of 16 and 18 months. The cases involving patients older than 5 years are extremely rare. The paper reports the case of female patient, who was diagnosed with hepatoblastoma in the age not typical for malignant neoplasms of this type. The review of hepatoblastoma epidemiology, possible risk factors, clinical manifestations, diagnosis and treatment methods is provided in this issue. 
Key words: hepatoblastoma, malignant tumor, liver lesion, alpha-fetoprotein.

About the Author

T.B. Tuyakova 1 , V.S. Rakhmetova 1 , G.A. Abai 1

1 Astana Medical University, Astana, Kazakhstan

References

1. https://www.inform.kz/ru/bolee-30-operaciy-po-udaleniyu-opuholi-iz-pecheni-detey-proveli-v-almaty-za-7-let_a3713740
2. Spector LG, Birch J. The epidemiology of hepatoblastoma. Pediatr Blood Cancer 2012;
3. Weinberg AG, Finegold MJ. Primary hepatic tumors of childhood. Hum Pathol 1983;
4. Khan A, Bader JL, Hoy GR et al. Hepatoblastoma in child with fetal alcohol syndrome. Lancet 1979.
5. Otten J, Smets R, De Jager R et al. Hepatoblastoma in an infant after contraceptive intake during pregnancey. N Engl J Med 1977.
6. Roll C, Luboldt HJ, Winter A et al. Hepatoblastoma in a 2-year-old child of a liver-transplanted mother. Lancet 1997.
7. Thomas J, George CR, Thomas P. A Case Report on Neonatal Hepatoblastoma. Journal of Pediatric Disorders and Neonatal Care. 2018.
8. Pichardo-Bahena R, Méndez-Sánchez N. Images in hepatology. Hepatoblastoma. Annals of Hepatology 2005.
9. de Campo M, de Campo J. F. Ultrasound of primary hepatic tumours in childhood. Pediatric Radiology 1988.
10. http://www.rcrz.kz/docs/clinic_protocol/2016/2пг/Педиатрия/
Гематология/1%20Гепатобластома%20у%20детей.pdf



For citation:Tuyakova T.B., Rakhmetova V.S., Abai G.A. Clinical case: Hepatoblastoma of the liver in the age not typical for hepatoblastoma. Clinical review for general practice. 2022; 3: 73–76. DOI: 10.47407/kr2022.3.3.00140


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