Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
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FULLSCREEN > Archive > 2022 > Vol 3, №6 (2022) > Laboratory diagnosis of pancreatic diseases

Laboratory diagnosis of pancreatic diseases

Ekaterina Yu. Plotnikova

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  • Abstract
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Abstract

Diseases of the pancreas in diagnosis are very problematic, since the symptoms are non-specific, and the training of doctors in the field of clinical pancreatology leaves much to be desired. With a incidence of 3–4/100 000 inhabitants and a prevalence of 10–40/100 000 inhabitants, chronic pancreatitis is a relatively common disease in industrialized countries. In our practice, we often encounter overdiagnosis of this pathology. CP represents the end of the continuum of diseases between acute and chronic pancreatitis. This article is intended to cover the basics of laboratory diagnostics of chronic pancreatitis and at the same time point to open questions for clinical research, expand the horizons of doctors, to timely determine both inflammatory processes in the pancreas and its exo- and endocrine insufficiency to prescribe adequate treatment. 
Key words: pancreatic diseases, chronic pancreatitis, acinar cell cytolysis markers, pancreonecrosis markers, pancreatic exocrine dysfunction markers, pancreatic endocrine dysfunction markers.

About the Author

Ekaterina Yu. Plotnikova 1

1 Kemerovo State Medical University, Kemerovo, Russia

References

1. Anaizi A, Hart PA, Conwell DL. Diagnosing Chronic Pancreatitis. Dig Dis Sci 2017; 62 (7): 1713–20. DOI: 10.1007/s10620-017-4493-2 
2. Steer ML, Waxman I, Freedman S. Chronic pancreatitis. N Engl J Med 1995; 332 (22): 1482–90. DOI: 10.1056/NEJM199506013322206 
3. Gupta V, Toskes P. Diagnosis and management of chronic pancreatitis. Postgrad Med J 2005; 81 (958): 491–7. DOI: 10.1136/pgmj.2003.009761 
4. Губергриц Н.Б. Возможности лабораторной диагностики заболеваний поджелудочной железы. Экспериментальная и клиническая гастроэнтерология. 2008; 7: 93–101. [Gubergrits N.B. Vozmozhnosti laboratornoi diagnostiki zabolevanii podzheludochnoi zhelezy. Ehksperimental'naya i klinicheskaya gastroehnterologiya. 2008; 7: 93–101 (in Russian).] 
5. Губергриц Н.Б., Христич Т.Н. Клиническая панкреатология. Донецк: Лебедь, 2000. [Gubergrits N.B., Khristich T.N. Klinicheskaya pankreatologiya. Donetsk: Lebed', 2000 (in Russian).] 
6. Lindkvist B. Diagnosis and treatment of pancreatic exocrine insufficiency. World J Gastroenterol 2013; 19 (42): 7258–66. DOI: 10.3748/wjg.v19.i42.7258 
7. Ивашкин В.Т. и др. Клинические рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению экзокринной недостаточности поджелудочной железы. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2018; 28 (2): 72–100. DOI: 10.22416/1382-4376-2018-28-2-72- 100 [Ivashkin V.T. et al. Klinicheskie rekomendatsii Rossiiskoi gastroehnterologicheskoi assotsiatsii po diagnostike i lecheniyu ehkzokrinnoi nedostatochnosti podzheludochnoi zhelezy. Rossiiskii zhurnal gastroehnterologii, gepatologii, koloproktologii. 2018; 28 (2): 72–100. DOI: 10.22416/1382-4376-2018-28-2-72-100 (in Russian).] 
8. Малых М.В., Дубцова Е.А., Винокурова Л.В. и др. Диагностика функциональной недостаточности поджелудочной железы. Эффективная фармакотерапия. 2021; 17 (4): 52–61. DOI: 10.33978/2307-3586-2021-17-4-52-61 [Malykh M.V., Dubtsova E.A., Vinokurova L.V. et al. Diagnostika funktsional'noi nedostatochnosti podzheludochnoi zhelezy. Ehffektivnaya farmakoterapiya. 2021; 17 (4): 52–61. DOI: 10.33978/2307- 3586-2021-17-4-52-61 (in Russian).] 
9. Электронный ресурс: http://www.invitro.ru/ [Ehlektronnyi resurs: http://www.invitro.ru/ (in Russian).] 
10. Электронный ресурс: https://studfile.net/preview/2766357/page: 194/ [Ehlektronnyi resurs: https://studfile.net/preview/2766357/page: 194/ (in Russian).] 
11. Электронный ресурс: https://helix.ru/kb/item/08-125 [Ehlektronnyi resurs: https://helix.ru/kb/item/08-125 (in Russian).] 
12. Электронный ресурс: https://medbe.ru/materials/podzheludochnaya-zheleza/otsenka-ekzokrinnoy-funktsii-podzheludochnoyzhelezy-bezzondovye-metody-diagnostiki-vneshnesekretorn/ [Ehlektronnyi resurs: https://medbe.ru/materials/podzheludochnaya-zheleza/otsenka-ekzokrinnoy-funktsii-podzheludochnoyzhelezy-bezzondovye-metody-diagnostiki-vneshnesekretorn/ (in Russian).] 
13. Freise J, Ranft U, Fricke K, Schmidt FW. Chronic pancreatitis: sensitivity, specificity and predictive value of the pancreolauryl test. Z Gastroenterol 1984; 22 (12): 705–12.

For citation:Plotnikova E.Yu. Laboratory diagnosis of pancreatic diseases. Clinical analysis in general medicine. 2022; 6: 24–29. DOI: 10.47407/kr2022.3.6.00172


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