Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
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FULLSCREEN > Archive > 2023 > Vol 4, №11 (2023) > Clinical case of gastroesophageal reflux disease of the fourth degree

Clinical case of gastroesophageal reflux disease of the fourth degree

Aleksandra V. Serezhkina , Irina G. Khmelevskaya , Natalya S. Razinkova , Irina I. Zhiznevskaya , Galina V. Shistilina , Elizaveta A. Romanova

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Abstract

Gastroesophageal reflux disease not only has a wide variety of clinical manifestations from the digestive system, but also affects other systems associated with it. due to the fact that this disease can occur under the mask of others, it is difficult to say how much it is widespread. due to the fourth degree of the disease, which is one of the most severe, the child needs the advice of a surgeon who will choose the tactics of further treatment and subsequent rehabilitation. Preventive measures for this pathology include: do not resort to tight swaddling, keep the baby in an upright position after feeding. 
Key words: children, gastroesophageal reflux disease, genetics, heredity, deletion, proton pump.

About the Author

Aleksandra V. Serezhkina , Irina G. Khmelevskaya , Natalya S. Razinkova , Irina I. Zhiznevskaya , Galina V. Shistilina , Elizaveta A. Romanova
Aleksandra V. Serezhkina1, Irina G. Khmelevskaya1, Natalya S. Razinkova1, Irina I. Zhiznevskaya1, Galina V. Shistilina2, Elizaveta A. Romanova1

1Kursk State medical university, Kursk, Russia; 
2Kursk Regional Children's Clinical Hospital, Kursk, Russia 
romanova.lisok@mail.ru

References

1. Orenstein SR, Shalaby TM, Finch R et al. Autosomal dominant infantile gastroesophageal reflux disease: exclusion of a 13q14 locus in five well characterized families. Am J Gastroenterol 2002; 97 (11): 2725–32. DOI: 10.1111/j.1572-0241.2002.07060.x. PMID: 12425539.
2. Ostrowski J, Rubel T, Wyrwicz LS et al. Three clinical variants of gastroesophageal reflux disease form two distinct gene expression signatures. J Mol Med (Berl) 2006; 84 (10): 872–82. DOI: 10.1007/s00109-006-0083-z. Epub 2006 Aug 4. PMID: 16924468.
3. Cheng X, Shi J, Zhang D et al. Assessing the genetic relationship between gastroesophageal reflux disease and chronic respiratory diseases: a mendelian randomization study. BMC Pulm Med 2023; 23 (1): 243. DOI: 10.1186/s12890-023-02502-8. PMID: 37403021; PMCID: PMC10318641.
4. Saitoh T, Otsuka H, Kawasaki T et al. Influences of CYP2C19 polymorphism on recurrence of reflux esophagitis during proton pump inhibitor maintenance therapy. Hepatogastroenterology 2009; 56 (91–92): 703–6. PMID: 19621685.
5. Федеральные кинические рекомендации по диагностике и лечению гастроэзофагеальной рефлюксной болезни у детей. 2015. Режим доступа: https://vodb2.vologda.ru/wp-content/uploads/2017/ 04/ГЭРБ.pdf
Federal clinical guidelines for the diagnosis and treatment of gastroesophageal reflux disease in children. 2015. Available at: https://vodb2.vologda.ru/wp-content/uploads/2017/04/GERD.pdf (in Russian).

For citation:Serezhkina A.V., Khmelevskaya I.G., razinkova n.S., Zhiznevskaya I.I., Shistilina G.V., romanova e.A. clinical case of gastroesophageal reflux disease of the fourth degree. Clinical review for general practice. 2023; 4 (11): 10–13 (In russ.). doI: 10.47407/kr2023.4.11.00295


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