Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
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FULLSCREEN > Archive > 2023 > Vol 4, №2 (2023) > Pauci-immune ANCA associated glomerulonephritis. Clinical case

Pauci-immune ANCA associated glomerulonephritis. Clinical case

Leonid I. Dvoretsky , Sergey A. Krivushkin , Nina A. Sidoruk , Ekaterina S. Stoliarevich , Svetlana E. Kolendo , Rosa M. Vakolyuk , Kira S. Papko

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Abstract

The female patient with extracapillary pauci-immune AncA associated glomerulonephritis having antibodies against myeloperoxidase and dialysis-requiring renal failure is described. The computed tomography revealed the mucous membrane thickening in the maxillary sinus. The pulse dose glucocorticosteroid and cyclophosphamide therapy contributed to the decrease in the levels of antibodies against myeloperoxidase and improvement of the nitrogen excretion function of the kidneys. 
Keywords: rapidly progressive glomerulonephritis, pauci-immune glomerulonephritis, diffuse extracapillary glomerulonephritis, AncA associated glomerulonephritis.

About the Author

Leonid I. Dvoretsky 1 , Sergey A. Krivushkin 2 , Nina A. Sidoruk 2 , Ekaterina S. Stoliarevich 3 , Svetlana E. Kolendo 1 , Rosa M. Vakolyuk 1 , Kira S. Papko 1

1 Sechenov First Moscow State medical university (Sechenov university), Moscow, Russia

2 Yudin city clinical Hospital, Moscow, Russia

3 City Clinical Hospital №52, Moscow, Russia

References

1. Jennette JC. Rapidly progressive crescentic glomerulonephritis. Kidney Int 2003; 63: 1164–77.
2. Lionaki S, Boletis J. The Prevalence and Management of Pauci-Immune Glomerulonephritis and Vasculitis in Western Countries. Kidney Dis 2015; 1: 224–34. DOI: 10.1159/000442062
3. Glassock RJ, Adler SG, Ward HJ et al. Primary glomerular diseases. In: The Kidney. Ed. B.M. Brenner, F.C. Rector. 4th. Philadelphia, Pa, USA: Saunders, 1991. P. 1182–279.
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6. Falk RJ. Jennette JC: Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 1988; 318: 1651–7.
7. Lionaki S, Blyth ER, Hogan SL et al. Classification of antineutrophil cytoplasmic autoantibody vasculitides:the role of antineutrophil cytoplasmic autoantibody specificity for myeloperoxidase or proteinase 3 in disease recognition and prognosis. Arthritis Rheum 2012; 64: 3452–62.
8. Rahmattulla C, de Lind van Wijngaarden RA, Berden AE et al. Renal function and ear, nose, throat involvement in anti-neutrophil cytoplasmic antibody-associated vasculitis: prospective data from the European Vasculitis Society clinical trials. Rheumatology 2015; 54 (5): 899–907. DOI: 10.1093/rheumatology/keu357
9. Watnick S, Dirkx T. Kidney disease. In: Current Medical Diagnosis & Treatment. Ed. M.A. Papadakis, S.J. McPhee, M.W. Rabow. New York, NY, 2015: McGraw-Hill; 2014.
10. Гордеев И.Г., Соболева В.Н., Волов Н.А. и др. Варианты течения быстропрогрессирующего гломерулонефрита: как и чем лечить. Лечебное дело. 2018; 1: 26–31. [Gordeev I.G., Soboleva V.N., Volov N.A. et al. Varianty techeniya bystroprogressiruyushchego glomerulonefrita: kak i chem lechit'. Lechebnoe delo. 2018; 1: 26–31 (in Russian).]

For citation:Dvoretsky L.I., Krivushkin S.A., Sidoruk n.A., Stoliarevich e.S., Kolendo S.e., Vakolyuk r.m., Papko K.S. Pauci-immune AncA associated glomerulonephritis. clinical case. clinical review for general practice. 2023; 4 (2): 31–35. doI: 10.47407/kr2023.4.2.00201


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