Abstract
Stomach cancer is an aggressive disease and represents a global health problem. Currently, more than 50% of patients with a newly diagnosed stomach cancer have a locally advanced process that requires a combined approach – a combination of surgical treatment and neoadjuvant/perioperative therapy. In a number of patients, after neoadjuvant therapy, there is a marked or even complete regression of the tumor; the prognosis of the disease, as well as the need for adjuvant therapy in this category of patients is the subject of discussion. This paper demonstrates the clinical observation of a complete clinical, radiological and morphological response after neoadjuvant therapy (2 cycles of chemotherapy FLOT + chemoradiotherapy), as well as long-term relapse-free survival in a patient with locally advanced gastric cancer.
Keywords: locally advanced gastric cancer, neoadjuvant therapy, complete tumor response, survival.
For citation:Mironova D.Yu., Skoropad V.Yu., Silanteva N.K., Agababian T.A., Zhavoronkova E.S., Ivanov S.A., Kaprin A.D. clinical observation of a complete clinical, radiological and pathomorphological response in a patient with locally advanced gastric adenocarcinoma after neoadjuvant therapy. Clinical review for general practice. 2024; 5 (7): 6-11. (In russ.). doI: 10.47407/kr2024.5.7.00442
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