Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
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FULLSCREEN > Archive > 2024 > Vol 5, №10 (2024) > Clinical case of anxiety-depressive disoreder in a patient with diagnoses «neurofibromatosis type 1» (Recklinghausen’s disease)

Clinical case of anxiety-depressive disoreder in a patient with diagnoses «neurofibromatosis type 1» (Recklinghausen’s disease)

E.N. Primysheva , A.S. Asanova , I.S.S. Bolotenyuk , M.A. Lepikhov , D.M. Berdieva , A.A. Dyachenko , M.S. Buziyan

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Abstract

This article describes a clinical case of anxiety-depressive disorder in a patient suffering from Neurofibromatosis type 1 (Recklinghausen's disease). Recklinghausen's disease is manifested by multiple neurofibromas along the peripheral nerves, in the form of painful rounded nodules in the thickness of the skin, varying in size and localization .The work is based on the study of the case history and analysis of hospitalizations of the patient (age 76), who was treated in the day hospital of the State Budgetary Healthcare Institution of the Republic of Crimea "Crimean Republican Clinical Psychiatric Hospital № 1 named after N.I. Balaban". An analysis of scientific literature devoted to the problem of Neurofibromatosis type 1 was conducted. As a result of studying the presented clinical case, it can be concluded that this category of patients is vulnerable to mental disorders. Neurologists and general practitioners caring for patients with Neurofibromatosis type 1 should be trained to recognize and regularly assess patients for the development of depression, a very common comorbid condition.
Keywords: Neurofibromatosis type 1, Recklinghausen's disease, anxiety-depressive disorder.

About the Author

E.N. Primysheva 1 , A.S. Asanova 1 , I.S.S. Bolotenyuk 1 , M.A. Lepikhov 1 , D.M. Berdieva 1 , A.A. Dyachenko 1 , M.S. Buziyan 1

1 Order of the Red Banner of Labor Georgievsky Medical Institute – a structural division of the Vernadsky Crimean Federal University, Simferopol, Russia

References

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2. Huson SM, Compston DA, Clark P, Harper P. A genetic study of von Recklinghausen neurofibromatosis in south east Wales. I. Prevalence, fitness, mutation rate, and effect of parental transmission on severity. J. med genetics. 1989;26(11):704-711. DOI: 10.1002/ajmg.a.33139
3. Ильина Р.Ю., Уракова Е.В., Нестеров О.В., Лексин Р.В. Клинический случай нейрофиброматоза Реклингхаузена. Практическая медицина. 2019;17(6, часть 2):64-66. DOI: 10.32000/2072-1757-2019-6-64-66)
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For citation:Stroevsky V.V., Primysheva E.N., Asanova A.Sh., Bolotenyuk I.S.S., Lepikhov M.A., Berdieva D.M., Dyachenko A.A., Buziyan M.S. Clinical case of anxiety-depressive disoreder in a patient with diagnoses «neurofibromatosis type 1» (Recklinghausen’s disease). Clinical review for general practice. 2024; 5 (10): 118–121 (In Russ.). DOI: 10.47407/kr2024.5.10.00505


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