Abstract
Oncolytic virotherapy is a promising treatment method that uses viruses to destroy cancer cells. This approach is particularly interesting in the context of the treatment of glioblastoma, one of the most aggressive forms of brain tumors. This therapy is based on the use of modified viruses capable of purposefully infecting and destroying tumor cells, while minimally affecting healthy tissues. The features of oncolytic virotherapy are the high specificity of viruses to cancer cells, which contributes to the activation of the body's immune response and increases therapeutic effectiveness. The use of oncolytic virotherapy for the treatment of glioblastoma is already yielding encouraging results in clinical trials and may be an important addition to traditional treatments such as surgery, radiotherapy and chemotherapy. In conclusion, oncolytic virotherapy is a promising approach to the treatment of glioblastoma, which requires further study to better understand its mechanisms of action and optimize its use in clinical practice.
Keywords: oncolytic virotherapy, tumor treatment, glioblastoma, oncology.
Keywords: oncolytic virotherapy, tumor treatment, glioblastoma, oncology.
For citation:Kaliberdenko V.B., Aramyan E.E., Zinchenko M.S. Features of oncolytic virotherapy and its application for the treatment of glioblastoma. Clinical review for general practice. 2024; 5 (12): 51–54 (In Russ.). DOI: 10.47407/kr2024.5.12.00537
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