Abstract
Background. Sweet’s syndrome (acute febrile neutrophilic dermatosis) is an extremely rare disease of the group of neutrophilic dermatoses with undulating courses of illness, which is an inflammatory non-infectious skin reaction characterized histopathologically by the presence of dense diffuse neutrophil infiltrate in the dermis without signs of leukocytoclastic vasculitis, edema and fragmentation of neutrophil nuclei. The mechanism of development of this disease is presumably associated with a cytokine-mediated hypersensitivity reaction followed by neutrophil infiltration of the dermis, however, the etiology of the development of this pathogenesis is not known. Sweet syndrome is a current problem, since complications can occur in the form of damage to the organs of the central nervous system, eyes, lungs, skin breakdown, as well as changes in the immune system in the form of immunodeficiency.
Aim. To evaluate, describe, study the courses and complications of the idiopathic form of Sweet’s syndrome.
Materials and methods. Study of examination data of a (3-year-old girld) who was being treated at the department of pulmonology of Kursk Regional Children's Clinical Hospital. Study and analysis of scientific literature on the problem of Sweet's syndrome.
Conclusion. As a result of studying this Clinical case, we came to the conclusion that despite the fact that Sweet’s syndrome is an extremely rare disease and more often debuts at the age of 60, it can also be observed in children, which must be taken into account in the presence of a skin rash without a known etiology and pathogenesis. Since complications may occur, it is necessary to identify and treat exacerbations of this disease in a timely manner. The prognosis of the disease is relatively favorable, since complications of Sweet’s syndrome can lead to a decrease in the quality of life of patients.
Keywords: children, skin diseases, Sweet’s syndrome, Clinical case.
Aim. To evaluate, describe, study the courses and complications of the idiopathic form of Sweet’s syndrome.
Materials and methods. Study of examination data of a (3-year-old girld) who was being treated at the department of pulmonology of Kursk Regional Children's Clinical Hospital. Study and analysis of scientific literature on the problem of Sweet's syndrome.
Conclusion. As a result of studying this Clinical case, we came to the conclusion that despite the fact that Sweet’s syndrome is an extremely rare disease and more often debuts at the age of 60, it can also be observed in children, which must be taken into account in the presence of a skin rash without a known etiology and pathogenesis. Since complications may occur, it is necessary to identify and treat exacerbations of this disease in a timely manner. The prognosis of the disease is relatively favorable, since complications of Sweet’s syndrome can lead to a decrease in the quality of life of patients.
Keywords: children, skin diseases, Sweet’s syndrome, Clinical case.
For citation:Stepin I.A., Serezhkina A.V., Khmelevskaya I.G., Minenkova T.A., Razinkova N.S. Clinical case of the idiopathic form of Sweet’s syndrome. Clinical review for general practice. 2024; 5 (4): 100–104 (In Russ.). DOI: 10.47407/kr2024.5.4.00426
All accepted articles publish licensed under a Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
