Clinical review for general practice

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FULLSCREEN > Archive > 2025 > Vol 6, №7 (2025) > Controlled ovarian stimulation in cancer patients: analysis of literature data on the use of antiestrogens and aromatase inhibitors

Controlled ovarian stimulation in cancer patients: analysis of literature data on the use of antiestrogens and aromatase inhibitors

Marina V. Kiseleva , Irina A. Yagovkina

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  • Abstract
  • About the Author
  • References

Abstract

Modern cancer treatments, including surgical interventions, chemotherapy and radiation therapy, often adversely affect reproductive function in women of childbearing age. This makes fertility preservation methods, particularly controlled ovarian stimulation, especially relevant. The article presents a comparative analysis of antiestrogens (Tamoxifen) and aromatase inhibitors (Letrozole) for ovulation induction in cancer patients. The efficacy, safety and specific features of these drugs in the context of fertility preservation are examined. 
Keywords: fertility preservation, oncological diseases, ovulation induction, Tamoxifen, Letrozole, reproductive medicine.

About the Author

Marina V. Kiseleva 1 , Irina A. Yagovkina 1

1 Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre, Obninsk, Russia

References

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65. Киселева М.В., Оразов М.Р., Пернай В.М. Методы сохранения фертильности у больных с серозными пограничными опухолями яичников. Клинический разбор в общей медицине. 2024;5(3):82-7. DOI: 10.47407/kr2023.5.3.00376 Kiseleva M.V., Orazov M.R., Pernay V.M. Methods to preserve fertility in patients with serous borderline ovarian tumors. Clinical review for general practice. 2024;5(3):82-7. DOI: 10.47407/kr2023.5.3.00376 (in Russian). 
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For citation: Kiseleva M.V., Yagovkina I.A. Controlled ovarian stimulation in cancer patients: analysis of literature data on the use of antiestrogens and aromatase inhibitors. Clinical review for general practice. 2025; 6 (7): 58–66 (In Russ.). DOI: 10.47407/kr2025.6.7.00645


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