Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
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FULLSCREEN > Archive > 2025 > Vol 6, №7 (2025) > Generalized sarcoidosis: difficulties in diagnosis and choice of treatment tactics

Generalized sarcoidosis: difficulties in diagnosis and choice of treatment tactics

Marina V. Lebedeva , Vladimir D. Beketov , Polina O. Mogilina , Marina V. Taranova , Ksenia V. Natarova

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  • Abstract
  • About the Author
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Abstract

The article presents a clinical case of a patient suffering from a chronic generalized sarcoidosis with lungs, intrathoracic lymph nodes, heart and kidneys involvement, the results of examination and treatment. 
Keywords: sarcoidosis, cardiac sarcoidosis, hyperglycemia.

About the Author

Marina V. Lebedeva 1 , Vladimir D. Beketov 1 , Polina O. Mogilina 2 , Marina V. Taranova 1 , Ksenia V. Natarova 1

1 Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia

2 Pirogov Russian National Research Medical University, Ministry of Health of Russia (Pirogov University), Moscow, Russia

References

1. Чучалин А.Г., Авдеев С.Н., Айсанов З.Р. и др. Саркоидоз: федеральные клинические рекомендации по диагностике и лечению. Пульмонология. 2022;32(6):806-33. DOI: 10.18093/0869-0189-2022-32-6-806-833 Chuchalin A.G., Avdeev S.N., Aisanov Z.R., et al. Sarcoidosis: federal clinical guidelines for diagnosis and treatment. Pul’monologiya. 2022;32(6):806-33. DOI: 10.18093/0869-0189-2022-32-6-806-833 (in Russian). 
2. Mathai SV, Patel S, Jorde UP, Rochlani Y. Epidemiology, Pathogenesis, and Diagnosis of Cardiac Sarcoidosis. Methodist Debakey Cardiovasc J. 2022 Mar 14;18(2):78-93. DOI: 10.14797/mdcvj.1057 
3. Farina N, De Luca G, Peretto G, et al. Cardiac Sarcoidosis: Clinical Insights, Diagnosis, and Management Strategies. Rev Cardiovasc Med. 2025 Feb 21;26(2):26605. DOI: 10.31083/RCM26605 
4. De Bortoli A, Birnie DH. Diagnosis and Treatment of Cardiac Sarcoidosis. Circ J. 2023 Mar 24;87(4):471-80. DOI: 10.1253/circj.CJ-22-0671 
5. Kwon S, Judson MA. Clinical Pharmacology in Sarcoidosis: How to Use and Monitor Sarcoidosis Medications. J Clin Med. 2024 Feb 22;13(5):1250. DOI: 10.3390/jcm13051250 
6. Liu A, Wang Y, Yan Y, et al. Renal sarcoidosis: renal pathology guides diagnosis and prognosis. Diagn Pathol. 2024 Dec 24;19(1):164. DOI: 10.1186/s13000-024-01591-1 
7. Язев Е.Е., Лебедева М.В., Стрижаков Л.А. и др. Желудочковая экстрасистолия как редкий дебют саркоидоза. Клиническая медицина. 2017;95(12):1137-40. DOI: 10.18821/0023-2149-2017-95-12-1137-1140 Yazev E.E., Lebedeva M.V., Strizhakov L.A., et al. Ventricular premature beats as a rare onset of sarcoidosis. Klinicheskaya meditsina. 2017;95(12):1137-40. DOI: 10.18821/0023-2149-2017-95-12-1137-1140 (in Russian).
8. Карпова О.Ю., Дворецкий Л.И. Поражение сердца при саркоидозе. Клинический разбор в общей медицине. 2020;(1):42-8. DOI: 10.47407/kr2020.1.1.00007 Karpova O.Yu., Dvoretsky L.I. Cardiac sarcoidosis manifestations. Clinical review for general practice. 2020;(1):42-8. DOI: 10.47407/ kr2020.1.1.00007 (in Russian). 
9. Dhooria S. Five principles and protocols for the clinician based on the 2021 ERS and BTS statements for treating sarcoidosis. Lung India. 2024 Nov 1;41(6):459-63. DOI: 10.4103/lungindia.lungindia_499_24 
10. Лебедева М.В., Чеботарева Н.В., Бекетов В.Д. Трудности диагностики и лечения поражения почек у пациента с генерализованным саркоидозом, перенесшего COVID-19. Терапевтический архив. 2022;94(6):769-71. DOI: 10.26442/00403660.2022.06.201566 Lebedeva M.V., Chebotareva N.V., Beketov V.D. Diagnostic and treatment difficulties in kidney damage in the patient with generalized sarcoidosis during COVID-19. Case report. Terapevticheskii arkhiv. 2022;94(6):769-71. DOI: 10.26442/00403660.2022.06.201566 (in Russian).

For citation: Lebedeva M.V., Beketov V.D., Mogilina P.O., Taranova M.V., Natarova K.V. Generalized sarcoidosis: difficulties in diagnosis and choice of treatment tactics. Clinical review for general practice. 2025; 6 (7): 87–91 (In Russ.). DOI: 10.47407/kr2025.6.7.00649


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