Dmitry I. Trukhan , Polina V. Shuganova , Igor N. Stepanov , Victoria V. Goloshubina , Andrey N. Navrotsky
Abstract
Asthenia/asthenic syndrome is present in the clinical picture of a large number of diseases and conditions, and, accordingly, the causes of asthenia are diverse. Acute respiratory viral infections are widespread diseases, poorly controlled infections, and are characterized by moderate, constant growth. Asthenia/asthenic syndrome after acute respiratory viral infection (post-viral asthenia) occupies a leading place in the structure of post-infectious asthenia and remains relevant in real clinical practice. In most patients, asthenic syndrome develops 10–14 days after recovery, and can persist for several months to six months. Due to the diverse clinical symptoms of post-viral asthenia, patients need complex therapy. The review examines one of its leading components – the use of vitamin and mineral complexes (nutraceuticals). The use of nutraceuticals in acute respiratory viral infections is experiencing a "second youth" due to new data accumulated during the pandemic of the new coronavirus infection (COVID-19). The review examines the possible impact of deficiency of trace elements selenium and zinc, vitamins A, E and C on various aspects of the course of acute respiratory viral infections: non-specific prevention, treatment and rehabilitation. The analysis of domestic and foreign literature indicates the benefits of including nutraceuticals in the complex therapy of asthenia/asthenic syndrome or chronic fatigue syndrome after acute respiratory viral infections (post-viral asthenia). In real clinical practice, it is advisable to supplement the recommendations of experts on the diagnosis of postinfectious asthenia by determining the levels of selenium and zinc and vitamins A, C, E in patients with asthenic syndrome and, with a reduced level of these components, consider prescribing vitamin and mineral complexes in order to eliminate the deficiency of essential micronutrients. The presence in the arsenal of a practitioner of the Selzink® vitamin and mineral complex at the outpatient stage of medical care will increase the effectiveness of rehabilitation of patients after acute respiratory viral infections in the presence of post-viral asthenia.
Keywords: asthenia, asthenic syndrome, chronic fatigue syndrome, acute respiratory viral infections, novel coronavirus infection (COVID-19), treatment, nutraceuticals, selenium, zinc, vitamin A, vitamin C, vitamin E, Selzink.
About the Author
Dmitry I. Trukhan 1 , Polina V. Shuganova 1 , Igor N. Stepanov 1 , Victoria V. Goloshubina 1 , Andrey N. Navrotsky 21 Omsk State Medical University, Omsk, Russia
2 Dalmatov Infectious diseases clinical hospital No. 1, Omsk, Russia
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For citation: Trukhan D.I., Shuganova P.V., Stepanov I.N., Goloshubina V.V., Navrotsky A.N. Nutraceuticals in the complex therapy of asthenic syndrome after acute respiratory viral infection. Clinical review for general practice. 2025; 6 (8): 78–85 (In Russ.). DOI: 10.47407/kr2025.6.8.00662
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