Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
  • Home
  • about
  • archives
  • contacts
left
FULLSCREEN > Archive > 2026 > Vol 7, №2 (2026) > Effectiveness of fertility restoration methods in women with polycystic ovary syndrome

Effectiveness of fertility restoration methods in women with polycystic ovary syndrome

Gulnara D. Matrizaeva , Gulzoda O. Rajabova , Gulchekhra A. Ikhtiyarova , Akbar O. Khaitov , Holidajon S. Ikramova

For citation:


  • Abstract
  • About the Author
  • References

Abstract

Polycystic ovary syndrome (PCOS) is one of the leading causes of endocrine infertility. This study evaluated the effectiveness of conservative, surgical, and combined treatment approaches for restoring reproductive function in women with PCOS.
Aim. To evaluate the effectiveness of various fertility restoration methods in patients with PCOS.
Materials and methods. A prospective study included 70 women with PCOS-associated infertility and 20 healthy controls. Patients were divided into three subgroups based on treatment approach. Clinical, hormonal, metabolic, and ultrasound parameters were analyzed.
Conclusion. Combined conservative and surgical treatment provided more stable and long-term fertility restoration compared to isolated surgical intervention.
Keywords: polycystic ovary syndrome, infertility, fertility restoration, laparoscopy, ovulation induction. 

About the Author

Gulnara D. Matrizaeva 1 , Gulzoda O. Rajabova 1 , Gulchekhra A. Ikhtiyarova 2 , Akbar O. Khaitov 1 , Holidajon S. Ikramova 1

1 Urgench State Medical Institute, Urgench, Uzbekistan

2 Abu Ali ibn Sino Bukhara State Medical Institute, Bukhara, Uzbekistan

References

1. Иванова А.Ю., Мохорт Т.В. Синдром поликистозных яичников: обновленные рекомендации международного научно обоснованного руководства 2023 года. М., 2024. 
Ivanova A.Yu., Mokhort T.V. Polycystic ovary syndrome: updated recommendations of the international scientifically based guidelines for 2023. Moscow, 2024. (in Russian).
2. Matrizayeva G.D, Ikramova X.S, Xaitov A.O. Assisment of quality of life indicators in hormonal infertility in women and determine the value of melatonin in treatment. Research journal of trauma and disability studies. 2022;01 (Issue: 10). ISSN: 2720–6866.
3. Матризаева Г.Д., Икрамова Х.С., Ражабова Г.О. Оценить кумулятивную эффективность стимуляции моноовуляции у женщин с синдромом Штейна Левенталя в различных возрастных группах. Тиббиетда янги кун. 2020;1(29):273-5. 
Matrizayeva G.D., Ikramova H.S., Razhabova G.O. To evaluate the cumulative effectiveness of monoovulation stimulation in women with Stein Leventhal syndrome in various age groups. Tibbietda yangi kun. 2020;1(29):273-5 (in Russian).
4. Можейко Л.Ф., Потоцкая А.А. Синдром поликистозных яичников: современный взгляд на проблему (обзор литературы). Репродуктивное здоровье. Восточная Европа. 2022;12(3):390-403. DOI: 10.34883/PI.2022.12.3.010
Mozheyko L.F., Potocka A.A. Polycystic ovary syndrome: a modern view of the problem (literature review). Reproductive health. Eastern Europe. 2022;12(3):390-403. DOI: 10.34883/PI.2022.12.3.010 (in Russian).
5. Адамян Л.В. и др. Синдром поликистозных яичников. Клинические рекомендации. Проблемы эндокринологии. 2022;68(2):112-27.
Adamyan L.V. et al. Polycystic ovary syndrome. Clinical recommendations. Problems of endocrinology. 2022;68(2):112-27 (in Russian).
6. Соснова, Е.А., Грачева, Т.С. Результаты хирургического лечения синдрома поликистозных яичников у женщин репродуктивного возраста. Архив акушерства и гинекологии им. В Ф. Снегирева. 2023;10(2):105-111. DOI: 10.17816/2313-8726-2023-10-2-105-111
7. Рязанова Д.Э., Иванова Е.Г. Современный взгляд на патогенез синдрома поликистозных яичников (обзор литературы). Вектор научной мысли. 2023;(5):5. 
Ryazanova D.E., Ivanova E.G. A modern view on the pathogenesis of polycystic ovary syndrome (literature review). The vector of scientific thought. 2023;(5):5 (in Russian).
Sosnova, E.A., Gracheva, T.S. Results of surgical treatment of polycystic ovary syndrome in women of reproductive age. Archive of Obstetrics and Gynecology named after V. F. Snegireva. 2023;10(2):105-111. DOI: 10.17816/2313-8726-2023-10-2-105-111 (in Russian).
8. Турчинец А.И. и др. Таргетная терапия синдрома поликистозных яичников. Медицинский совет. 2023;17(5):7-13. 
Turchinets A.I. and others. Targeted therapy of polycystic ovary syndrome. Medical advice. 2023;17(5):7-13. (in Russian).
9. Xie J et al. The role of lncRNA HUPCOS in androgen metabolism and follicle growth arrest in polycystic ovary syndrome. Cell Biology and Toxicology. 2025;41(1):105.

For citation:Matrizaeva G.D., Rajabova G.O., Ikhtiyarova G.A., Khaitov A.O., Ikramova Kh.S. Effectiveness of fertility restoration methods in women with polycystic ovary syndrome. Clinical review for general practice. 2026; 7 (2): 84–91 (In Russ.). DOI: 10.47407/kr2026.7.2.00773


All accepted articles publish licensed under a Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

  • About
  • Editorial board
  • Ethics
  • For authors
  • Author fees
  • Peer review
  • Contacts

oa
crossref
анри


  Indexing

Scopus
doaj
elibrary

Address of the Editorial Office:

127055, Moscow, s/m 37

Correspondence address:

115054, Moscow, Zhukov passage, 19, fl. 2, room XI


Managing Editor:

+7 (495) 926-29-83

id@con-med.ru