Abstract
Relevance. As is known, the functioning of the thyroid gland is closely related to the metabolism of iodine and depends on the sufficiency or excess of its intake. Therefore, both endogenous and exogenous factors can affect iodine metabolism and, indirectly, the function of the thyroid gland. Clinical manifestations of disorders, regardless of their genesis, have similar features, and the management of patients requires a fundamentally different approach. In these cases, it is the timely and correct differential diagnosis that determines the patient's future.
Aim. To share the experience of a differentiated approach to the diagnosis of diseases and conditions caused by disorders of iodine metabolism in order to establish the cause of these disorders, using the example of a presented clinical case.
Materials and methods. The data of a 59-year-old patient who was referred for examination and treatment with manifestations of hyperthyroidism are presented. The data of the conducted research (ultrasound, thyroid-stimulating hormone, free thyroxine) confirmed the disorder of the thyroid function, but an additional study – determination of the density of the thyroid gland using computed tomography (RCT) – was required for the differential diagnosis of the disease genesis.
Results. To clarify the cause of the disorder of iodine metabolism (increased consumption or excessive intake of iodine), a study of the density of the thyroid gland was carried out. This method revealed a high density of the thyroid gland, confirming the excessive accumulation of iodine in the organ, which is possible only with an excessive intake of exogenous iodine into the body.
Conclusion. Modern methods of diagnosing thyroid dysfunction can be supplemented by RCT in cases where it is necessary to perform differential diagnostics of the genesis of the detected disorders and promptly optimize therapeutic approaches.
Keywords: iodine metabolism, iodine-induced diseases, X-ray computed tomography, hyperthyroidism.
For citation:Sargar R.V., Kurnikova I.A., Tomashevsky I.O., Meleshkevich T.A., Zhuravleva A.S., Kukhareva E.I. To the problem of differential diagnosis of amiodarone-induced hyperthyroidism. Clinical review for general practice. 2026; 7 (6): 37–40 (In Russ.). DOI: 10.47407/kr2026.7.6.00878
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