Clinical review for general practice

ISSN (Print) 2713-2552
ISSN (Online) 2782-5671
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FULLSCREEN > Archive > 2021 > Vol 2, №7 (2021) > The Clinical Case of Lactate-acidosis with Fatal Outcome in a Patient with 2 Type Diabetes

The Clinical Case of Lactate-acidosis with Fatal Outcome in a Patient with 2 Type Diabetes

Olga Yu. Ibragimova , Diana Sh. Avzaletdinova , Tatiana V. Morugova , Elena R. Vlasova , Nataliya G. Kharina , Zukhra G. Girfanova

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  • Abstract
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Abstract

At the moment, lactate-acidosis coma in patients with diabetes mellitus is considered a rare and extremely urgent condition that occurs in patients with concomitant diseases as well as when taking the most widely used sugar reducing drug – metformin. This article describes a case of lactate-acidosis coma with a fatal outcome, which occurred against the background of taking metformin and alcohol abuse, in a woman with type 2 dia-betes mellitus aged 48 years. 

Key words: type 2 diabetes, lactate-acidosis, metformin, alcohol.

About the Author

Olga Yu. Ibragimova 1 2 , Diana Sh. Avzaletdinova 1 , Tatiana V. Morugova 1 , Elena R. Vlasova 2 , Nataliya G. Kharina 2 , Zukhra G. Girfanova 2

1 Bashkir State Medical University, Ufa, Russia

2 City Clinical Hospital №21, Ufa, Russia

References

1. Скворцов В.В., Скворцова Е.М., Бангаров Р.Ю. Лактат-ацидоз в практике врача ‒ анестезиолога-реаниматолога. Вестник анестезиологии и реаниматологии. 2020; 17 (3): 95–100. DOI: 10.21292/2078-5658-2020-17-3-95-100
2. Альфонсова Е.В., Забродина Л.А. Роль ацидоза в механизмах формирования полиорганной недостаточности. Ученые за-писки Забайкальского государственного университета (Био-логические науки). 2014; 1 (54).
3. Standards of specialized diabetes care. Edited by I.I. Dedov, M.V. Shestakova, A.Yu. Mayorov. 10th Edition. Moscow, 2021. DOI: 10.14341/DM12802 (in Russian).
4. Dedov I.I., Melnichenko G.А. Endokrinologiya. Natsionalnoye rukovodstvo. [Endocrinology. National Guidelines]. Moscow: GEO-TAR-Media Publ., 2013 (in Russian).
5. Dedov I.I., Shestakova M.V. Sakharny diabet: ostrye i khronich-eskie oslozhneniya. Moscow: Meditsinskoe Informatsionnoye Agentstvo, 2011 (in Russian).
6. Renda F, Mura P, Finco G et al. Metformin-associated lactic acidosis requiring hospitalization. A national 10 year survey and a system-atic literature review. Eur Rev Med Pharmacol Sci 2013; 17 (Suppl. 1): 45–9.
7. Blagosklonnaia Ia.V., Shliakhto E.V., Babenko A.Iu. Endokrinologi-ia: uchebnik dlia vuzov. Saint Petersburg: SpetsLit, 2012. P. 325–26 (in Russian).
8. Shestakova M.V., Dedov I.I. Sakharnyi diabet i khronicheskaia bolezn' pochek. Moscow: MIA, 2009. P. 263–95 (in Russian).
9. Mkrtumian A.M., Nelaeva A.A. Neotlozhnaia endokrinologiia: uchebnoe posobie. Moscow: GEOTAR-Media, 2008. P. 98–107 (in Russian).

For citation:Ibragimova O.Y., Avzaletdinova D.S., Morugova T. V. et al. The Clinical Case of Lactate-acidosis with Fatal Outcome in a Patient with 2 Type Diabetes. Clinical review for general practice. 2021; 7: 7: 35–39. DOI: 10.47407/kr2021.2.7.00086


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